| 2025-11-13 00:00:00November 13, 2025 | Fort White Indians | BYE | 2025 Week 13 Football Schedule | 2025 | N/A |
| 2025-11-13 00:00:00November 13, 2025 | Moore Haven Terriers | BYE | 2025 Week 13 Football Schedule | 2025 | N/A |
| 2025-11-13 00:00:00November 13, 2025 | Northview Chiefs | BYE | 2025 Week 13 Football Schedule | 2025 | N/A |
| 2025-11-13 00:00:00November 13, 2025 | Port St. Joe Tiger Sharks | BYE | 2025 Week 13 Football Schedule | 2025 | N/A |
| 2025-11-13 00:00:00November 13, 2025 | Holmes County Blue Devils | BYE | 2025 Week 13 Football Schedule | 2025 | N/A |
| 2025-11-13 00:00:00November 13, 2025 | Union County Tigers | BYE | 2025 Week 13 Football Schedule | 2025 | N/A |
| 2025-11-13 00:00:00November 13, 2025 | Miami B.T. Washington Tornadoes | BYE | 2025 Week 13 Football Schedule | 2025 | N/A |
| 2025-11-13 00:00:00November 13, 2025 | Hallandale Chargers | BYE | 2025 Week 13 Football Schedule | 2025 | N/A |
| 2025-11-13 00:00:00November 13, 2025 | Land O' Lakes Gators | BYE | 2025 Week 13 Football Schedule | 2025 | N/A |
| 2025-11-13 18:00:00November 13, 2025 | Oasis  | 24 - 0 | Inlet Grove Hurricanes | 2025 | N/A |
| 2025-11-13 18:30:00November 13, 2025 | Dr. Joaquin Garcia Bulldogs | 55 - 33 | Sarasota Sailors | 2025 | N/A |
| 2025-11-13 18:30:00November 13, 2025 | Palm Beach Lakes Rams | 0 - 32 | Royal Palm Beach Wildcats | 2025 | N/A |
| 2025-11-13 18:30:00November 13, 2025 | Palm Beach Gardens Gators | 29 - 8 | Centennial | 2025 | N/A |
| 2025-11-13 19:00:00November 13, 2025 | Miami Palmetto Panthers | 42 - 0 | Coral Glades Jaguars | 2025 | N/A |
| 2025-11-13 19:00:00November 13, 2025 | Buchholz  | 49 - 41 |  Oviedo | 2025 | N/A |
| 2025-11-13 19:00:00November 13, 2025 | Mosley Dolphins | 33 - 30 | Lincoln Trojans | 2025 | N/A |
| 2025-11-13 19:00:00November 13, 2025 | Booker Tornadoes | 75 - 0 | Mulberry Panthers | 2025 | N/A |
| 2025-11-13 19:00:00November 13, 2025 | Lely Trojans | 52 - 26 | Estero Wildcats | 2025 | N/A |
| 2025-11-13 19:00:00November 13, 2025 | Immaculata-La Salle Royal Lions | 42 - 7 | Somerset Academy Silver Palms Stallions | 2025 | N/A |
| 2025-11-13 19:00:00November 13, 2025 | Milton Central | 28 - 20 | Wewahitchka Gators | 2025 | N/A |
| 2025-11-13 19:00:00November 13, 2025 | Dunnellon  | 34 - 20 | Pensacola Fighting Tigers | 2025 | N/A |
| 2025-11-13 19:00:00November 13, 2025 | Weeki Wachee Hornets | 19 - 44 | Andrew Jackson Tigers | 2025 | N/A |
| 2025-11-13 19:00:00November 13, 2025 | Hudson Cobras | 42 - 0 | Tenoroc Titans | 2025 | N/A |
| 2025-11-13 19:00:00November 13, 2025 | Miramar Patriots | 8 - 14 | Westwood Academy Panthers | 2025 | N/A |
| 2025-11-13 19:30:00November 13, 2025 | Northwestern Bulls | 70 - 0 | Somerset Academy Pines Panthers | 2025 | N/A |
| 2025-11-13 19:30:00November 13, 2025 | Jefferson County Tigers | 12 - 28 | Wildwood Wildcats | 2025 | N/A |
| 2025-11-13 19:30:00November 13, 2025 | Palatka  | 52 - 20 | Wolfson Wolfpack | 2025 | N/A |
| 2025-11-13 19:30:00November 13, 2025 | Palm Harbor University | 24 - 41 | Chiles Timberwolves | 2025 | N/A |
| 2025-11-13 19:30:00November 13, 2025 | Matanzas  | 37 - 42 |  Bartram Trail | 2025 | N/A |
| 2025-11-13 19:30:00November 13, 2025 | Tate Aggies | 35 - 14 | First Coast | 2025 | N/A |
| 2025-11-14 00:00:00November 14, 2025 | NMB Chargers | BYE | | 2025 | N/A |
| 2025-11-14 14:30:00November 14, 2025 | Gulliver Prep Raiders | 13 - 20 | Ransom Everglades Raiders | 2025 | N/A |
| 2025-11-14 15:30:00November 14, 2025 | Edison Red Raiders | 50 - 7 | Westminster Christian Warriors | 2025 | N/A |
| 2025-11-14 18:00:00November 14, 2025 | Santaluces Chiefs | 3 - 28 |  Columbus Explorers | 2025 | N/A |
| 2025-11-14 18:30:00November 14, 2025 | Jupiter Christian  | 39 - 37 |  NSU University | 2025 | N/A |
| 2025-11-14 18:30:00November 14, 2025 | Delray Beach American Heritage  | 53 - 18 |  Space Coast | 2025 | N/A |
| 2025-11-14 18:30:00November 14, 2025 | Spanish River Sharks | 23 - 21 | Western Wildcats | 2025 | N/A |
| 2025-11-14 18:30:00November 14, 2025 | Mandarin Mustangs  | 42 - 14 | Crestview Bulldogs | 2025 | N/A |
| 2025-11-14 18:30:00November 14, 2025 | Ed White Commanders | 41 - 20 | Pine Forest Eagles | 2025 | N/A |
| 2025-11-14 18:30:00November 14, 2025 | Raines Vikings | 43 - 6 | Baker County Wildcats | 2025 | N/A |
| 2025-11-14 18:30:00November 14, 2025 | Glades Central Raiders | 23 - 6 | The King's Academy Lions | 2025 | N/A |
| 2025-11-14 18:30:00November 14, 2025 | Pahokee Blue Devils | 43 - 28 | Fort Meade Miners | 2025 | N/A |
| 2025-11-14 18:30:00November 14, 2025 | Chaminade-Madonna Lions  | 63 - 0 | Boca Raton St. John Paul II Eagles | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Mount Dora Christian  | 50 - 18 |  Foundation Academy | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | The Master's Academy  | 34 - 51 |  Oak Hall | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Cambridge Christian  | 24 - 21 |  St. Edward's | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | West Nassau  | 20 - 10 |  Fernandina Beach | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Bradenton Christian  | 28 - 12 |  Academy At The Lakes | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Real Life Christian  | 49 - 26 |  Merritt Island Christian | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | All Saints Academy  | 46 - 22 |  First Coast Christian | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | The Classical Academy  | 60 - 73 |  St. Francis | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Boone  | 19:00:007:00 pm |  Winter Park | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Boone | 24 - 12 | Winter Park | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Vero Beach Fighting Indians | 57 - 10 |  East Ridge | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Southridge Spartans | 49 - 0 | Nova Titans | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Flanagan Falcons | 12 - 24 | Piper Bengals | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Ponte Vedra  | 31 - 30 | Niceville Eagles | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Mater Academy Lions | 20 - 49 | Coconut Creek Cougars | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Bolles Bulldogs | 63 - 13 | Walton Braves | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | South Walton Seahawks | 42 - 3 | Freeport Bulldogs | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | The Villages Charter  | 28 - 35 |  Berkeley Prep Buccaneers | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Cardinal Mooney Cougars  | 55 - 7 | North Broward Prep Eagles | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Carol City Chiefs | 21 - 38 | Killian Cougars | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Baker Gators | 35 - 0 | Liberty County Bulldogs | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Cardinal Newman Crusaders | 37 - 0 | Benjamin Buccaneers | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Saint Andrew's Scots | 64 - 20 | Archbishop Carroll Bulldogs | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | True North Classical Academy Titans | 42 - 17 | Palmer Trinity | 2025 | N/A |
| 2025-11-14 19:00:00November 14, 2025 | Bishop McLaughlin  | 13 - 25 |  Windermere Prep | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Spruce Creek  | 19:30:007:30 pm |  Sanford Seminole | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Lake Mary  | 19:30:007:30 pm |  Hagerty | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | DeLand  | 70 - 21 |  Creekside | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Spruce Creek | 23 - 20 | Sanford Seminole | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Lake Mary | 42 - 14 | Hagerty | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Venice Indians  | 49 - 12 | Ridge Community Bolts | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | West Orange  | 45 - 30 | Plant City Raiders | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Sumner Stingrays | 44 - 13 |  Ocoee | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Sarasota Riverview Rams | 42 - 13 | Winter Haven Blue Devils | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | St. Cloud  | 0 - 29 |  Lake Nona | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Fort Pierce Central Cobras | 28 - 27 | Palm Beach Central Broncos | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Jupiter Warriors | 21 - 24 |  Dr. Phillips | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Nease  | 45 - 7 |  Oakleaf | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Pace Patriots | 20 - 6 |  Evans | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Armwood Fighting Hawks | 43 - 0 |  Melbourne | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Viera  | 54 - 13 | Riverview Sharks | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Kissimmee Osceola  | 20 - 15 | Durant Cougars | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | South Lake  | 37 - 36 | Plant Panthers | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Palmetto Tigers | 42 - 41 | Wiregrass Ranch Bulls | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Mitchell Mustangs | 40 - 9 | Lennard Longhorns | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | East Lake Eagles | 35 - 7 | Parrish Community Bulls | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | West Boca Raton Bulls | 35 - 7 | Largo Packers | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Monarch Knights | 39 - 0 | Doral Academy Firebirds | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | West Broward Bobcats | 56 - 13 | South Plantation Paladins | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Beachside  | 23 - 7 | Milton Panthers | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Mainland  | 34 - 13 |  Middleburg | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Edgewater  | 33 - 0 | Lake Gibson Braves | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Tampa Bay Tech Titans | 47 - 6 | Sebring Blue Streaks | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Gaither Cowboys | 56 - 0 |  Winter Springs | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Lakeland Dreadnaughts  | 35 - 0 | Wesley Chapel Wildcats | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Riverdale Raiders | 47 - 22 | North Fort Myers Red Knights | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Immokalee Indians | 10 - 8 | Pinellas Park Patriots | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Manatee Hurricanes | 28 - 21 | Charlotte Tarpons | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Cape Coral Seahawks | 35 - 21 | Gulf Coast Sharks | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | St. Thomas Aquinas Raiders  | 58 - 7 |  Heritage | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Martin County Tigers | 13 - 41 | McArthur Mustangs | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Delray Beach Atlantic Eagles | 55 - 0 | North Miami Pioneers | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | St. Augustine  | 70 - 21 | Arnold Marlins | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Columbia Tigers | 35 - 0 | Rickards Raiders | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Choctawhatchee Indians | 49 - 6 | Pensacola B.T. Washington Wildcats | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Jones  | 35 - 13 |  Deltona | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Vanguard  | 21 - 14 | Auburndale Bloodhounds | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | New Smyrna Beach  | 3 - 38 | Lake Wales Highlanders | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Zephyrhills Bulldogs | 35 - 0 |  Rockledge | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Tampa Jesuit Tigers | 62 - 0 | Seminole Osceola | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Naples Golden Eagles | 21 - 13 | South Fort Myers Wolfpack | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Clearwater Tornadoes | 45 - 6 | Blake Yellow Jackets | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Port Charlotte Pirates | 48 - 21 | Dunbar Tigers | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Archbishop McCarthy Mavericks | 49 - 6 | Hialeah Thoroughbreds | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Jensen Beach Falcons | 14 - 49 |  Norland Vikings | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Dillard Panthers | 14 - 21 | Plantation Colonels | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Plantation American Heritage Patriots | 50 - 20 | John Carroll Golden Rams | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Yulee Hornets | 16 - 24 | West Florida Jaguars | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Bishop Kenny Crusaders | 43 - 19 | Wakulla War Eagles | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Bay Tornadoes | 43 - 56 | Godby Cougars | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Bishop Moore  | 61 - 6 | Hernando Leopards | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Eastside  | 42 - 15 | South Sumter Raiders | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Merritt Island  | 41 - 13 |  Titusville | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Eau Gallie  | 26 - 0 |  Tavares | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Chamberlain Chiefs | 12 - 27 | Bayshore Bruins | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Jefferson Dragons | 41 - 40 | Boca Ciega Pirates | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Nature Coast Tech Sharks | 7 - 0 | Gibbs Gladiators | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Cypress Lake Panthers | 34 - 44 | Key West Conchs | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Miami Central Rockets | 70 - 0 | Saint Brendan Sabres | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Florida High Seminoles | 42 - 31 | Baldwin Indians | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Pensacola Catholic Crusaders | 48 - 0 | Bozeman Bucks | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Bradford  | 55 - 6 | Avon Park Red Devils | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Cocoa  | 42 - 13 |  Newberry | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Clearwater Calvary Christian Warriors | 34 - 30 |  Santa Fe | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Fort Lauderdale Calvary Christian Eagles | 14 - 22 | Bishop Verot Vikings | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Somerset Academy Canyons Cougars | 7 - 52 | Lakewood Spartans | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Cardinal Gibbons Chiefs | 48 - 28 | Monsignor Pace Spartans | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Blountstown Tigers | 38 - 0 | Jay Royals | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Chipley Tigers | 8 - 43 |  Madison County | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Taylor County | 28 - 7 | Trenton Tigers | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Chiefland Indians | 44 - 6 | Sneads Pirates | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Williston Red Devils | 42 - 14 |  Lafayette | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Hawthorne  | 42 - 0 | Branford Buccaneers | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | University Chrisitan | 55 - 14 |  Trinity Catholic | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Episcopal School Eagles | 0 - 36 |  Impact Christian Academy | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Maclay Marauders | 39 - 18 | NFEI Eagles | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Jacksonville Trinity Christian | 42 - 16 | Providence School Stallions | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Carrollwood Day Patriots | 70 - 3 |  Father Lopez | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Melbourne Central Catholic  | 21 - 4 |  Orlando Christian Prep | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Lakeland Christian Vikings | 31 - 33 | Victory Christian Storm | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Clearwater Central Catholic Marauders  | 45 - 0 | Indian Rocks Christian Golden Eagles | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | St. Petersburg Catholic Barons | 50 - 14 | Evangelical Christian Sentinels | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Southwest Florida Christian Academy King's | 0 - 41 | St. John Neumann Celtics | 2025 | N/A |
| 2025-11-14 19:30:00November 14, 2025 | Community School of Naples Seahawks | 63 - 13 | Northside Christian Mustangs | 2025 | N/A |
| 2025-11-15 18:00:00November 15, 2025 | Glades Day  | 21 - 24 |  Rocky Bayou Christian | 2025 | N/A |
| 2025-11-15 19:30:00November 15, 2025 | Goleman Gators | 30 - 28 | South Dade Buccaneers | 2025 | N/A |
