| 2022-10-11 19:00:33October 11, 2022 | Loughborough(ENG, UK) NFL Academy | 14 - 26 | IMG Academy Varsity White Ascenders | 2022 | N/A |
| 2022-10-10 19:00:58October 10, 2022 | Colonial  | 0 - 44 |  Timber Creek | 2022 | N/A |
| 2022-10-10 19:00:52October 10, 2022 | New Smyrna Beach  | 21 - 25 |  CFCA | 2022 | N/A |
| 2022-10-10 19:00:29October 10, 2022 | Kissimmee Gateway  | 27 - 0 |  Liberty | 2022 | N/A |
| 2022-10-10 19:00:29October 10, 2022 | Evans  | 13 - 8 |  Lake Brantley | 2022 | N/A |
| 2022-10-10 19:00:27October 10, 2022 | Winter Springs  | 3 - 42 |  Lyman | 2022 | N/A |
| 2022-10-10 19:00:19October 10, 2022 | Lake Buena Vista  | 3 - 48 |  Horizon | 2022 | N/A |
| 2022-10-10 19:00:18October 10, 2022 | Tohopekaliga  | 2 - 31 |  Bishop Moore | 2022 | N/A |
| 2022-10-10 19:00:08October 10, 2022 | Orlando Freedom  | 21 - 6 |  Oak Ridge | 2022 | N/A |
| 2022-10-10 19:00:07October 10, 2022 | Lake Minneola  | 49 - 7 |  West Port | 2022 | N/A |
| 2022-10-10 19:00:03October 10, 2022 | Wekiva  | 6 - 14 |  Edgewater | 2022 | N/A |
| 2022-10-10 18:30:32October 10, 2022 | Fivay Falcons | 34 - 41 |  East Ridge | 2022 | N/A |
| 2022-10-10 18:00:49October 10, 2022 | Crescent City  | 48 - 7 |  Taylor | 2022 | N/A |
| 2022-10-10 18:00:02October 10, 2022 | South Lake  | 6 - 35 |  Forest | 2022 | N/A |
| 2022-10-10 18:00:01October 10, 2022 | Jones  | 18 - 7 |  Kissimmee Osceola | 2022 | N/A |
| 2022-10-08 14:00:45October 8, 2022 | FSDB Dragons | 22 - 50 | Talladega(AL) AIDB Silent Warriors | 2022 | N/A |
| 2022-10-07 19:30:33October 7, 2022 | The Master's Academy Eagles | 32 - 0 | Legacy Charter Eagles | 2022 | N/A |
| 2022-10-07 19:30:25October 7, 2022 | Bolles Bulldogs | 42 - 12 | TRU Prep Academy Saints | 2022 | N/A |
| 2022-10-07 19:30:23October 7, 2022 | Fort White Indians | 23 - 21 |  Lafayette | 2022 | N/A |
| 2022-10-07 19:30:05October 7, 2022 | Seven Rivers Christian Warriors | 51 - 0 | First Academy Eagles | 2022 | N/A |
| 2022-10-07 19:00:59October 7, 2022 | Manatee Hurricanes | 19:00:59Canceled |  Rockledge | 2022 | N/A |
| 2022-10-07 19:00:58October 7, 2022 | DeLand  | 58 - 42 |  Deltona | 2022 | N/A |
| 2022-10-07 19:00:58October 7, 2022 | USCEDEA Stars | 19:00:587:00 pm | Peniel Academy Warriors | 2022 | N/A |
| 2022-10-07 19:00:57October 7, 2022 | Menendez  | 6 - 20 |  Tocoi Creek | 2022 | N/A |
| 2022-10-07 19:00:56October 7, 2022 | West Nassau Warriors | 16 - 12 |  P.K. Yonge | 2022 | N/A |
| 2022-10-07 19:00:56October 7, 2022 | Oasis Christian Lions | 40 - 0 | Eastland Christian Hurricanes | 2022 | N/A |
| 2022-10-07 19:00:55October 7, 2022 | Anclote Sharks | 0 - 36 | Umatilla Bulldogs | 2022 | N/A |
| 2022-10-07 19:00:54October 7, 2022 | Williston Red Devils | 63 - 6 |  Lake Weir | 2022 | N/A |
| 2022-10-07 19:00:54October 7, 2022 | St. John Lutheran Saints | 8 - 22 | The Classical Academy Patriots | 2022 | N/A |
| 2022-10-07 19:00:53October 7, 2022 | Taylor | 0 - 44 |  Interlachen Rams | 2022 | N/A |
| 2022-10-07 19:00:51October 7, 2022 | Tohopekaliga | 53 - 14 | Wesley Chapel Wildcats | 2022 | N/A |
| 2022-10-07 19:00:51October 7, 2022 | Destin Sharks | 14 - 20 | Bozeman Bucks | 2022 | N/A |
| 2022-10-07 19:00:50October 7, 2022 | Tradition Prep Pirates | 0 - 68 | Port St. Lucie Jaguars | 2022 | N/A |
| 2022-10-07 19:00:49October 7, 2022 | Bishop Kenny Crusaders | 31 - 32 |  Ponte Vedra | 2022 | N/A |
| 2022-10-07 19:00:49October 7, 2022 | Bell Bulldogs | 19:00:497:00 pm | Riverside Christian School Wranglers | 2022 | N/A |
| 2022-10-07 19:00:48October 7, 2022 | Orange Park  | 7 - 26 | Columbia Tigers | 2022 | N/A |
| 2022-10-07 19:00:48October 7, 2022 | Countryside Christian Minutemen | 53 - 26 | Ocala Christian Crusaders | 2022 | N/A |
| 2022-10-07 19:00:47October 7, 2022 | Hawthorne  | 21 - 12 | Gibbs Gladiators | 2022 | N/A |
| 2022-10-07 19:00:45October 7, 2022 | Faith Christian Academy Lions | 7 - 28 |  Father Lopez | 2022 | N/A |
| 2022-10-07 19:00:45October 7, 2022 | Trinity Catholic  | 49 - 46 | Clearwater Calvary Christian Warriors | 2022 | N/A |
| 2022-10-07 19:00:44October 7, 2022 | Blountstown Tigers | 0 - 49 | Northview Chiefs | 2022 | N/A |
| 2022-10-07 19:00:44October 7, 2022 | Wewahitchka Gators | 0 - 34 | Liberty County Bulldogs | 2022 | N/A |
| 2022-10-07 19:00:44October 7, 2022 | Fort Meade Miners | 54 - 0 | Ambassadors Christian Academy Stallions | 2022 | N/A |
| 2022-10-07 19:00:43October 7, 2022 | Belleview  | 0 - 18 |  Dunnellon | 2022 | N/A |
| 2022-10-07 19:00:41October 7, 2022 | Spruce Creek  | 38 - 7 | Atlantic Coast Stingrays | 2022 | N/A |
| 2022-10-07 19:00:41October 7, 2022 | Bishop Snyder Cardinals | 6 - 35 | Westminster Academy Lions | 2022 | N/A |
| 2022-10-07 19:00:40October 7, 2022 | Middleburg  | 41 - 12 |  Clay County | 2022 | N/A |
| 2022-10-07 19:00:40October 7, 2022 | Santa Fe  | 0 - 40 | Suwannee Bulldogs | 2022 | N/A |
| 2022-10-07 19:00:38October 7, 2022 | Leesburg  | 22 - 34 | Forest | 2022 | N/A |
| 2022-10-07 19:00:37October 7, 2022 | Mainland  | 37 - 0 |  Orange City University | 2022 | N/A |
| 2022-10-07 19:00:37October 7, 2022 | Palatka  | 61 - 8 | Space Coast Vipers | 2022 | N/A |
| 2022-10-07 19:00:37October 7, 2022 | Cocoa Beach Minutemen | 35 - 0 | Cornerstone Charter Ducks | 2022 | N/A |
| 2022-10-07 19:00:36October 7, 2022 | Fort Myers Canterbury Cougars | 19:00:36Canceled | Community School of Naples Seahawks | 2022 | N/A |
| 2022-10-07 19:00:34October 7, 2022 | Sebastian River Sharks | 7 - 30 |  Heritage | 2022 | N/A |
| 2022-10-07 19:00:34October 7, 2022 | American Collegiate Academy Rough Riders | 19:00:347:00 pm | Roar Prep & Vocational Academy Lions | 2022 | N/A |
| 2022-10-07 19:00:34October 7, 2022 | Carrollwood Day Patriots | 6 - 20 | Rockledge | 2022 | N/A |
| 2022-10-07 19:00:33October 7, 2022 | Foundation Academy  | 23 - 7 | Orangewood Christian Rams | 2022 | N/A |
| 2022-10-07 19:00:32October 7, 2022 | Citrus Hurricanes | 0 - 49 | West Port | 2022 | N/A |
| 2022-10-07 19:00:32October 7, 2022 | Bayside Bears | 21 - 14 |  Viera | 2022 | N/A |
| 2022-10-07 19:00:32October 7, 2022 | Lakeside Christian Lions | 47 - 42 | Sarasota Christian Blazers | 2022 | N/A |
| 2022-10-07 19:00:31October 7, 2022 | Branford Buccaneers | 46 - 0 | Trenton Tigers | 2022 | N/A |
| 2022-10-07 19:00:31October 7, 2022 | Port St. Joe Tiger Sharks | 48 - 0 | Vernon Yellow Jackets | 2022 | N/A |
| 2022-10-07 19:00:29October 7, 2022 | Trinity Prep Saints | 0 - 34 |  The First Academy | 2022 | N/A |
| 2022-10-07 19:00:29October 7, 2022 | Windermere Prep Lakers | 12 - 31 | Lake Highland Prep Highlanders | 2022 | N/A |
| 2022-10-07 19:00:28October 7, 2022 | Taylor County Bulldogs | 48 - 0 | Lighthouse PCA Stingrays | 2022 | N/A |
| 2022-10-07 19:00:26October 7, 2022 | Eastside  | 35 - 10 |  Ridgeview | 2022 | N/A |
| 2022-10-07 19:00:26October 7, 2022 | Vanguard  | 17 - 18 |  North Marion | 2022 | N/A |
| 2022-10-07 19:00:26October 7, 2022 | Harvest Community School Warriors | 3 - 41 | Oak Hall Eagles | 2022 | N/A |
| 2022-10-07 19:00:25October 7, 2022 | CFCA | 42 - 7 | St. Edward's Pirates | 2022 | N/A |
| 2022-10-07 19:00:25October 7, 2022 | Berkeley Prep Buccaneers  | 44 - 7 | IMG Academy Varsity White Ascenders | 2022 | N/A |
| 2022-10-07 19:00:25October 7, 2022 | Cedar Creek Christian Saints | 34 - 20 | Eagle's View Academy Warriors | 2022 | N/A |
| 2022-10-07 19:00:25October 7, 2022 | Sarasota Riverview Rams | 19:00:25Canceled | Kissimmee Osceola | 2022 | N/A |
| 2022-10-07 19:00:24October 7, 2022 | Fernandina Beach Pirates | 39 - 8 | Paxon Golden Eagles | 2022 | N/A |
| 2022-10-07 19:00:23October 7, 2022 | Santa Fe Catholic Hawks | 26 - 0 | Roar Prep & Vocational Academy Lions | 2022 | N/A |
| 2022-10-07 19:00:22October 7, 2022 | Flagler Palm Coast  | 20 - 35 |  Eau Gallie | 2022 | N/A |
| 2022-10-07 19:00:21October 7, 2022 | St. Augustine  | 58 - 41 |  Nease | 2022 | N/A |
| 2022-10-07 19:00:21October 7, 2022 | Sanford Seminole  | 35 - 29 |  Cocoa | 2022 | N/A |
| 2022-10-07 19:00:20October 7, 2022 | Bell Creek Academy Panthers | 16 - 29 | Out-Of-Door Academy Thunder | 2022 | N/A |
| 2022-10-07 19:00:19October 7, 2022 | Fleming Island  | 19:00:19Canceled | Lake Minneola | 2022 | N/A |
| 2022-10-07 19:00:18October 7, 2022 | Melbourne  | 24 - 0 |  Palm Bay | 2022 | N/A |
| 2022-10-07 19:00:18October 7, 2022 | Crescent City | 38 - 18 |  Keystone Heights | 2022 | N/A |
| 2022-10-07 19:00:17October 7, 2022 | Kissimmee Gateway | 6 - 44 |  St. Cloud | 2022 | N/A |
| 2022-10-07 19:00:16October 7, 2022 | New Smyrna Beach | 20 - 9 | Sunlake Seahawks | 2022 | N/A |
| 2022-10-07 19:00:16October 7, 2022 | Cambridge Christian Lancers | 43 - 0 | Bradenton Christian Panthers | 2022 | N/A |
| 2022-10-07 19:00:16October 7, 2022 | St. Petersburg Canterbury Crusaders | 6 - 46 | Shorecrest Prep Chargers | 2022 | N/A |
| 2022-10-07 19:00:16October 7, 2022 | Lake Mary  | 36 - 16 | NMB Chargers | 2022 | N/A |
| 2022-10-07 19:00:14October 7, 2022 | Beachside  | 65 - 6 | Impact Christian Academy Lions | 2022 | N/A |
| 2022-10-07 19:00:13October 7, 2022 | Astronaut  | 21 - 7 | Winter Springs | 2022 | N/A |
| 2022-10-07 19:00:11October 7, 2022 | St. Joseph Academy Flashes | 30 - 0 | St. Francis Catholic Wolves | 2022 | N/A |
| 2022-10-07 19:00:10October 7, 2022 | Harmony  | 3 - 24 |  Hagerty | 2022 | N/A |
| 2022-10-07 19:00:07October 7, 2022 | Merritt Island Christian Cougars  | 7 - 48 | Donahue Academy Shamrocks | 2022 | N/A |
| 2022-10-07 19:00:07October 7, 2022 | Halifax Academy  | 42 - 6 | Bishop McLaughlin Hurricanes | 2022 | N/A |
| 2022-10-07 19:00:07October 7, 2022 | Poinciana  | 32 - 21 | Davenport Broncos | 2022 | N/A |
| 2022-10-07 19:00:06October 7, 2022 | Titusville  | 32 - 7 |  Port Orange Atlantic | 2022 | N/A |
| 2022-10-07 19:00:06October 7, 2022 | Saint Stephen's Episcopal Falcons | 8 - 14 | St. Petersburg Catholic Barons | 2022 | N/A |
| 2022-10-07 19:00:05October 7, 2022 | Boca Raton Christian Blazers | 56 - 14 | Jordan Christian Prep Seahawks | 2022 | N/A |
| 2022-10-07 19:00:05October 7, 2022 | Satellite  | 21 - 28 |  Seabreeze | 2022 | N/A |
| 2022-10-07 19:00:05October 7, 2022 | Bishop Moore | 50 - 27 | Braden River Pirates | 2022 | N/A |
| 2022-10-07 19:00:04October 7, 2022 | IMG Academy National Ascenders | 45 - 0 | Milwaukee(WI) St. Thomas More Cavaliers | 2022 | N/A |
| 2022-10-07 19:00:02October 7, 2022 | Madison County Cowboys  | 20 - 39 | CAI Knights | 2022 | N/A |
| 2022-10-07 19:00:00October 7, 2022 | Pine Ridge  | 0 - 42 |  Mount Dora | 2022 | N/A |
| 2022-10-07 19:00:00October 7, 2022 | Deltona Trinity Christian Academy Eagles | 6 - 28 | Bronson Eagles | 2022 | N/A |
| 2022-10-07 19:00:00October 7, 2022 | Bartram Trail  | 17 - 0 | Fleming Island | 2022 | N/A |
| 2022-10-07 18:30:38October 7, 2022 | Jupiter Christian School Eagles | 49 - 6 | Somerset Prep Hurricanes | 2022 | N/A |
| 2022-10-07 18:30:08October 7, 2022 | Stanton Prep Blue Devils | 7 - 35 | Wolfson Wolfpack | 2022 | N/A |
| 2022-10-07 18:00:54October 7, 2022 | West Oaks Academy  | 8 - 18 | American Collegiate Academy Rough Riders | 2022 | N/A |
| 2022-10-07 17:30:40October 7, 2022 | Real Life Christian Raptors | 6 - 44 | Old Plank Christian Defenders | 2022 | N/A |
| 2022-10-07 16:30:47October 7, 2022 | Geneva Classical Academy Knights | 7 - 48 |  Gainesville Christian Warriors | 2022 | N/A |
| 2022-10-07 16:00:16October 7, 2022 | Hernando Christian Lions | 56 - 14 | Hope Christian Lions | 2022 | N/A |
| 2022-10-07 16:00:13October 7, 2022 | Foundation Christian Panthers | 10 - 32 | Four Corners Charter Coyotes | 2022 | N/A |
| 2022-10-06 19:00:57October 6, 2022 | Windermere  | 0 - 41 | Wekiva | 2022 | N/A |
| 2022-10-06 19:00:56October 6, 2022 | Edgewater | 40 - 0 | Timber Creek | 2022 | N/A |
| 2022-10-06 19:00:52October 6, 2022 | East Ridge | 14 - 43 | Lyman | 2022 | N/A |
| 2022-10-06 19:00:46October 6, 2022 | Jones | 62 - 0 |  Orlando University | 2022 | N/A |
| 2022-10-06 19:00:46October 6, 2022 | Dr. Phillips  | 27 - 14 |  Lake Nona | 2022 | N/A |
| 2022-10-06 19:00:44October 6, 2022 | Ocoee  | 31 - 28 |  Winter Park | 2022 | N/A |
| 2022-10-06 19:00:39October 6, 2022 | Oak Ridge | 6 - 47 | Evans | 2022 | N/A |
| 2022-10-06 19:00:39October 6, 2022 | Orlando Cypress Creek  | 20 - 27 | Horizon | 2022 | N/A |
| 2022-10-06 19:00:37October 6, 2022 | IMG Academy Varsity Blue Ascenders | 21 - 42 | Golden Gate Titans | 2022 | N/A |
| 2022-10-06 19:00:36October 6, 2022 | Apopka  | 38 - 23 |  Olympia | 2022 | N/A |
| 2022-10-06 19:00:34October 6, 2022 | Oakleaf  | 48 - 49 |  Creekside | 2022 | N/A |
| 2022-10-06 19:00:32October 6, 2022 | Lake Howell  | 27 - 21 | Lake Buena Vista | 2022 | N/A |
| 2022-10-06 19:00:25October 6, 2022 | All Saints Academy Saints | 40 - 0 | Master's Academy Patriots | 2022 | N/A |
| 2022-10-06 19:00:19October 6, 2022 | Buchholz  | 49 - 0 |  Gainesville | 2022 | N/A |
| 2022-10-06 19:00:15October 6, 2022 | Eustis  | 35 - 45 |  Merritt Island | 2022 | N/A |
| 2022-10-06 19:00:11October 6, 2022 | Avant Garde Sharks | 38 - 6 | Palm Beach Christian Saints | 2022 | N/A |
| 2022-10-06 19:00:00October 6, 2022 | East River  | 43 - 0 | Colonial | 2022 | N/A |
| 2022-10-06 16:00:05October 6, 2022 | Duval Charter School Panthers | 8 - 20 | Lake Mary Prep Griffins | 2022 | N/A |
